Iain Chapple and colleagues from University of Birmingham, United Kingdom appear to have made a notable discovery. They have confirmed natural immunity followed by the first Pfizer shot produces an enduring antibody response. We link to their ‘Longitudinal Protection Following Natural SARS-CoV-2 Infection and Early Vaccine Responses’ at the end of this post.
Immunity Gained After Natural Infection Plus the Boost
Iain Chapple and his associates’ findings may be particularly relevant for dentists and other medical professionals working close to their patients faces. They noticed increased antibody response after the first Pfizer shot, compared to subjects with natural immunity.
The research involved 873 participants, who volunteered their blood samples after natural infection followed by vaccination. Just over half of these received their first dose of the Pfizer vaccine, and the rest a placebo according to Medical News and Life Sciences. There was a 49% increase in the subject’s antibody response, compared to study participants not previously exposed to the COVID-19 disease.
Reviewing Natural Immunity After the First Pfizer Shot
Only time will tell how long this enhanced immunity will last. None the less, this discovery may help governments delay the second Pfizer shot until all their citizens have received their first one.
It could also be helpful input in poorer countries with high infection rates, and low budgets. And presumably more abundant antibodies in the general population.
There is, however no proven evidence of vaccines granting permanent immunity from COVID-19. And therefore long-lasting relief from the acute respiratory syndrome associated with the disease. At best, it seems likely the vaccine will only temporarily boost natural immunity after a previous infection. And so we continue on our search for a permanent solution.
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Preview Image: Primary Immune Response Processes
